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Tramadol is a strong painkiller from a group of medicines called opiates, or narcotics. It's used to treat moderate to severe pain, for example after an operation or a serious injury. If you have long term pain, your doctor may also prescribe it if weaker painkillers no longer work.

It does not stop the pain completely, but you will not be able to feel it as much.

It is available only on prescription. It comes as tablets, capsules and liquid drops that you swallow. It can also be given by injection, but this is usually only done in hospital.

  • It's possible to become addicted to this drug, but your doctor will explain how to reduce those risks.

  • If you need to take this drug for more than a few weeks, your treatment plan may include details of how and when to stop taking this medicine.

  • It's best not to drink alcohol with Tramadol as you're more likely to get side effects, like feeling sleepy.

  • Do not drive a car, ride a bike or use tools or machinery if it makes you sleepy, dizzy, or clumsy or you have blurred vision or are unable to concentrate or make decisions.

  • Tramadol is also called by the brand names Invodol, Larapam, Mabron, Maneo, Oldaram, Tilodol, Tradorec and Zeridame.

How to use Tramadol HCL

Before You Begin

  • Always review the Medication Guide provided with each prescription and refill. It contains essential instructions on how to use and safely dispose of tramadol. If anything is unclear, talk to your doctor or pharmacist.

How to Use Tramadol

  • Follow your doctor’s instructions closely—take the medication by mouth as prescribed, usually every 4–6 hours only as needed for pain.

  • You may take it with or without food. If nausea occurs, try taking tramadol with meals or ask your provider about other strategies to ease nausea (for example, lying down with minimal head movement).

  • If using the liquid form, use the measuring device provided (e.g., syringe or spoon). Household utensils aren’t accurate and could lead to incorrect dosing—ask your pharmacist if unsure.

Dosing and Adjustments

  • Dosing is personalized based on your health and how well the pain is managed. To reduce side effects, your doctor may start you on a low dose and gradually increase it.

  • For immediate-release tramadol: typically 50–100 mg every 4–6 hours as needed for pain, with a maximum of 400 mg per day.

  • For older adults (over 75), the ceiling is usually 300 mg per day.

  • Extended-release forms (for chronic pain) are usually taken once daily, with a maximum of 300 mg per day, and must be swallowed whole (do not crush or split them). 

  • Never exceed your prescribed dose or the duration recommended by your healthcare provider.

Effective Timing

  • Pain relievers like tramadol are most effective when taken at the first sign of pain. Waiting until the pain peaks may reduce its effectiveness.

  • If you have chronic pain, your doctor may prescribe a long-acting opioid and use tramadol only for occasional “breakthrough” pain. Other treatments like acetaminophen or ibuprofen could also be part of your plan—check with your healthcare provider about combining them safely.

Avoiding Withdrawal

  • Do not stop tramadol abruptly, especially if used long-term or in high doses—this can lead to withdrawal symptoms. Your doctor will typically taper your dose gradually.

  • Seek medical guidance promptly if you experience withdrawal symptoms like restlessness, mood changes, sleep disturbances, runny nose, nausea, diarrhea, muscle aches, or unusual behavior.

What to Do If the Medication Stops Working

  • Over time, tramadol may become less effective. If you notice this, talk to your doctor before making any changes to your dosage.

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