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Naloxone for sale online. It is administered for the treatment of opioid toxicity, specifically to reverse respiratory depression from opioid use. This drug is useful in accidental or intentional overdose and acute or chronic toxicity. Common substance overdoses treated with this drug include heroin, fentanyl, carfentanil, hydrocodone, oxycodone, and methadone.
The Centers for Disease Control and Prevention (CDC) issued an alert in October 2015 reporting an increase in fentanyl-related accidental overdose deaths due to illicitly manufactured fentanyl. In August 2016, the CDC updated its previous alert after a sharp rise in the availability of counterfeit opioid pills sold on the street containing varying amounts of fentanyl and other similar compounds.
According to the American Heart Association (AHA), most opioid overdoses progress to out-of-hospital arrest (OA-OHCA) due to loss of airway patency and respiratory insufficiency. Therefore, alongside it's administration, it is crucial to address respiratory failure to stabilize the individual
Naloxone is usually administered intravenously. However, if IV access can't be achieved, it can also be administered via an intraosseous (IO), subcutaneous (SQ), intramuscular (IM), or intranasal (NAS) route. When administered intravenously, it completely reverses the effects of opioids within a few minutes. This is available as an injectable solution in concentrations of 0.4 mg/mL and 1 mg/mL and a high-dose (5 mg/0.5 mL) prefilled syringe. An intranasal formulation of naloxone is available as a solution in concentrations of 3 mg/0.1 mL actuation, 4 mg/0.1 mL actuation, and 8 mg/0.1 mL actuation.
How to use Naloxone HCL Vial
This medication is given by injection into a muscle or under the skin. It may also be given by injection into a vein, usually by a health care professional.
If you are using this medication at home, learn all preparation and usage instructions from your health care professional and the product package. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Learn how to store and discard medical supplies safely. Close family and household members should know the symptoms of an opioid overdose and be instructed on how to give naloxone if needed. Opioid overdose should be treated right away to prevent serious effects (such as brain damage). See also Uses section.
The dosage is based on your medical condition and response to treatment.
The effects of this medication are rapid but not long-lasting. After giving naloxone, get medical help right away, even if the person wakes up. If symptoms return after giving an injection, give another naloxone injection every 2 to 3 minutes. Continue to closely watch the person until emergency help is received. Tell the healthcare professional that you have given an injection of naloxone.
Precautions
Before using naloxone, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart problems (such as irregular heartbeat, previous heart attack).
Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
Since untreated opioid overdose can harm both a pregnant woman and her unborn baby, this medication may be used during pregnancy. However, naloxone may cause opioid withdrawal in your unborn baby. Tell your doctor right away that you used this medication, so you and your unborn baby can be monitored. Ask your doctor for details.
It is unknown if this medication passes into breast milk. However, it is unlikely to harm a nursing infant. Consult your doctor before breastfeeding.
Adult Dosage
The dose is titrated to increase the patient's respiratory drive and allow for adequate spontaneous respiration and oxygenation, but not full reversal. This can result in withdrawal and include combative or aggressive behavior. A small initial IV dose (usually 0.04 mg to 0.1 mg) is recommended in patients who are opioid-dependent with symptoms of opioid overdose to avoid opioid withdrawal symptoms. Larger initial doses (such as 0.4 mg) are recommended in patients without a known history of opioid dependency. In patients who present with apnea or near-apnea with cyanosis, especially in the prehospital setting, providers should not hesitate to administer larger initial doses, such as 1 mg to 2 mg IV or 2mg intranasal, IM, or SQ. Clinicians can administer subsequent doses of 0.1 mg to 0.4 mg IV or 0.4 mg to 1 mg NAS, IM, or SQ in any opioid overdose patient until reaching the desired effect. Opioids for sale online at great prices without prescription.